The moment index of minima (II)

The moment index of a nonnegative random variable X has the property that the moment index of the minimum of two independent r.v.s X and Y is greater than or equal to the sum of the moment indices of X and Y. We characterize conditions under which equality holds for a given r.v. X and every independent nonnegative r.v. Y, and discuss extensions to related r.v.s and their distributions

Dynamics of Rumor Spreading in Complex Networks

We derive the mean-field equations characterizing the dynamics of a rumor process that takes place on top of complex heterogeneous networks. These equations are solved numerically by means of a stochastic approach. First, we present analytical and Monte Carlo calculations for homogeneous networks and compare the results with those obtained by the numerical method. Then, we study the spreading process in detail for random scale-free networks. The time profiles for several quantities are numerically computed, which allow us to distinguish among different variants of rumor spreading algorithms. Our conclusions are directed to possible applications in replicated database maintenance, peer to peer communication networks and social spreading phenomena.Comment: Final version to appear in PR

Fault-Tolerant Dissipative Preparation of Atomic Quantum Registers with Fermions

We propose a fault tolerant loading scheme to produce an array of fermions in an optical lattice of the high fidelity required for applications in quantum information processing and the modelling of strongly correlated systems. A cold reservoir of Fermions plays a dual role as a source of atoms to be loaded into the lattice via a Raman process and as a heat bath for sympathetic cooling of lattice atoms. Atoms are initially transferred into an excited motional state in each lattice site, and then decay to the motional ground state, creating particle-hole pairs in the reservoir. Atoms transferred into the ground motional level are no longer coupled back to the reservoir, and doubly occupied sites in the motional ground state are prevented by Pauli blocking. This scheme has strong conceptual connections with optical pumping, and can be extended to load high-fidelity patterns of atoms.Comment: 12 pages, 7 figures, RevTex

Investigations into the Sarcomeric Protein and Ca2+-Regulation Abnormalities Underlying Hypertrophic Cardiomyopathy in Cats (Felix catus).

Hypertrophic cardiomyopathy (HCM) is the most common single gene inherited cardiomyopathy. In cats (Felix catus) HCM is even more prevalent and affects 16% of the outbred population and up to 26% in pedigree breeds such as Maine Coon and Ragdoll. Homozygous MYBPC3 mutations have been identified in these breeds but the mutations in other cats are unknown. At the clinical and physiological level feline HCM is closely analogous to human HCM but little is known about the primary causative mechanism. Most identified HCM causing mutations are in the genes coding for proteins of the sarcomere. We therefore investigated contractile and regulatory proteins in left ventricular tissue from 25 cats, 18 diagnosed with HCM, including a Ragdoll cat with a homozygous MYBPC3 R820W, and 7 non-HCM cats in comparison with human HCM (from septal myectomy) and donor heart tissue. Myofibrillar protein expression was normal except that we observed 20–44% MyBP-C haploinsufficiency in 5 of the HCM cats. Troponin extracted from 8 HCM and 5 non-HCM cat hearts was incorporated into thin filaments and studied by in vitro motility assay. All HCM cat hearts had a higher (2.06 ± 0.13 fold) Ca2+-sensitivity than non-HCM cats and, in all the HCM cats, Ca2+-sensitivity was not modulated by troponin I phosphorylation. We were able to restore modulation of Ca2+-sensitivity by replacing troponin T with wild-type protein or by adding 100 μM Epigallocatechin 3-gallate (EGCG). These fundamental regulatory characteristics closely mimic those seen in human HCM indicating a common molecular mechanism that is independent of the causative mutation. Thus, the HCM cat is a potentially useful large animal model

Quantum Field Theory for the Three-Body Constrained Lattice Bose Gas -- Part II: Application to the Many-Body Problem

We analyze the ground state phase diagram of attractive lattice bosons, which are stabilized by a three-body onsite hardcore constraint. A salient feature of this model is an Ising type transition from a conventional atomic superfluid to a dimer superfluid with vanishing atomic condensate. The study builds on an exact mapping of the constrained model to a theory of coupled bosons with polynomial interactions, proposed in a related paper [11]. In this framework, we focus by analytical means on aspects of the phase diagram which are intimately connected to interactions, and are thus not accessible in a mean field plus spin wave approach. First, we determine shifts in the mean field phase border, which are most pronounced in the low density regime. Second, the investigation of the strong coupling limit reveals the existence of a new collective mode, which emerges as a consequence of enhanced symmetries in this regime. Third, we show that the Ising type phase transition, driven first order via the competition of long wavelength modes at generic fillings, terminates into a true Ising quantum critical point in the vicinity of half filling.Comment: 22 pages, 5 figure

Bounds and comparisons of the loss ratio in queues driven by an M/M/∞ source.

We obtain upper bounds for the loss probability in a queue driven by an M/M/∞ source. The bound is compared with exact numerical results, and with bounds for two related arrivals models: superposed two state Markov fluids, and the Ornstein—Uhlenbeck process. The bounds are shown to behave continuously through approximation procedures relating the models

Spreading of Persistent Infections in Heterogeneous Populations

Up to now, the effects of having heterogeneous networks of contacts have been studied mostly for diseases which are not persistent in time, i.e., for diseases where the infectious period can be considered very small compared to the lifetime of an individual. Moreover, all these previous results have been obtained for closed populations, where the number of individuals does not change during the whole duration of the epidemics. Here, we go one step further and analyze, both analytically and numerically, a radically different kind of diseases: those that are persistent and can last for an individual's lifetime. To be more specific, we particularize to the case of Tuberculosis' (TB) infection dynamics, where the infection remains latent for a period of time before showing up and spreading to other individuals. We introduce an epidemiological model for TB-like persistent infections taking into account the heterogeneity inherent to the population structure. This sort of dynamics introduces new analytical and numerical challenges that we are able to sort out. Our results show that also for persistent diseases the epidemic threshold depends on the ratio of the first two moments of the degree distribution so that it goes to zero in a class of scale-free networks when the system approaches the thermodynamic limit.Comment: 12 pages and 2 figures. Revtex format. Submitted for publication

Observability of Quantum Criticality and a Continuous Supersolid in Atomic Gases

We analyze the Bose-Hubbard model with a three-body hardcore constraint by mapping the system to a theory of two coupled bosonic degrees of freedom. We find striking features that could be observable in experiments, including a quantum Ising critical point on the transition from atomic to dimer superfluidity at unit filling, and a continuous supersolid phase for strongly bound dimers.Comment: 4 pages, 2 figures, published version (Editor's suggestion